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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9efdf8c57c33cf1981cabda2057f8d72e21a7bb7779023e0eb2280e2cebe762b' 
  AND token = '2a7gSqmV6DJV9B9J7GnaOByk2ZyjrcuQ2YgGfhKopVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}