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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8889548bd00352be8eba5c8e52313fd2935e3905b5af16517286d1d8dacb8751' 
  AND token = 'Rqjgl5X3m/6AO0TT900KS3zi4NRUqcKFwTy/oi/o8Vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}