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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1715ddc62c183b4cee0e9ac0efd3eba5fe290e42a872a16a8d0e738f4153130b' 
  AND token = 'NHI+mTEB3IKdOulKzhxEHBsa3Fl0F/P0LtGHz+mjUpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}