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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a5c664f8a1232a1185c366953584b54cada3fd6b5f367aad04ec34ee7e5aa68' 
  AND token = 'A1qWKCaYzJISU160zmL5FSCDlmyMhyAoXEEoG9xf8/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}