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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28c25b54c68b876e9e0f651556c153b37940d04eec2a71c1ccae070c2c8507ec' 
  AND token = 'YkDeqyffniFIGHqpoxj8PxNCcCRYreVAlQcK5zWCKxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}