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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b1b465971dee651ac3f0a246daac32f9fb445eb5f2f294b11bed2171c9486ad' 
  AND token = 'hm/5//KhYA3YE4aJOV7vi+lbXI2sDcPMDE+4SXe3Ndc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}