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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4d3bcd24397853a9d8430a0cd43f088f7a57ec87e68e317c4a0de23c2b9aaa0' 
  AND token = 'HWyf89On2hgc3I0go10E3fuqk6LSTaQg7kBOZE0d+zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}