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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b33b6dc6239f837d564a131a63484ec9358edf45db33f5b21a8ebf8716ad780d' 
  AND token = 'CCEwohRar0y0Z5s2oalwtf12R3S7LJSZAiJBz7+Iyq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}