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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bf5e77281aa646459c74c01e9d34d243cb10403b3cad7d381eae5d02361d3f4' 
  AND token = 'N1GJd3DK1sz3Q0gjxWEz3Uwk5PgiroKTq6FnZhvRgao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}