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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45cadbc916572d0b3ff69fef1d1d6b4a2734bdb3bbaf8e8b7a320710fb77ddfe' 
  AND token = 'ZRo5BZe9gF6B0CCIP1fj9MYdU8R4vyQWjiesevMoXtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}