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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a259ece03d032fb22bc34e4d63667750d3b9f25befec4a602ddc592295fb2721' 
  AND token = 'Cw5MBMw9PbBc/xiEKiRvYrlKlCAqz93ksdVniyoPtCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}