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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8ce44339b09dd075f226e0245b879bffb7ea6c3d2da63b119bf95d3c0bfd5b4' 
  AND token = 'PjF9iQ6PNWESWV/LcRS1Y8vocPN0KXcXsAhZFMSTe4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}