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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9241f5cb0aa3b87f7f976963a49c8f626acedc1da8370e34318cf25fbbe2a3e8' 
  AND token = 'KxbkMFYo8ZATSeRk5Sl1cYcxllqV9wtMoWNP22wbXM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}