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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fada32d93eb361b4cc2febbf8f659ed744621d82651d4bd9a6d7b2ee1c0deff' 
  AND token = 'pLPj/8gV1Y8kMAB8mEYfLPWTn10qhTHD+6qfrwe0ydc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}