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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4da23314a75496249a78e67d9e7f7f979ddacd88187cea78bf038067d1b7c14c' 
  AND token = 'y6Ui4M0Pd3ML44lwDVue3Zrm7tQyLXfZPw+Dn9zAUMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}