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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f43207506a6d11ab3e7e0c5c3b5bdab83f994c4092aa8005de66f582b0efd630' 
  AND token = 's6+fsL+dkgFq9rMLOYEXLyDnRWtUaU4D6nShPw2FJ6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}