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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2378b974a4560b95c22e56ab9ae1183a0235b4d92279226be321fbea6f61ed06' 
  AND token = 'EEwwZmKxTHpSas771w88Qcy0Rsd3YZ8SPSeCsxF5Z2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}