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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f4957ba1d499f4ad44dd35cf66e9317df6d269af00f75d3d253006bb468b424' 
  AND token = 'd4Lk5gNQScSTq5gjTRYsqVavu1A88e5GFWMe+rFa5FA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}