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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9226486eee1d1b16e9124b0f7052fa5cabfa184911998cb980ae495313ea27d' 
  AND token = '4532XIvRBU71s7PfH+FMB4H5Y/L+7MNu6L1lA4dbQwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}