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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e03c485f4c6ed3aed44843a08bb649e7a06f72ac20736ef81b24fefa3d3288c0' 
  AND token = 'T/s7p0ef/VMc4vQtIZ/8e4zcHHajwy3IjA2oFbzkAp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}