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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d25ec6abaa29370a85c0559aed5b0f82491f870888f1d76d78994e2b484d518' 
  AND token = 'f1Q2UYyxGkECtqgNv5aW2/+/o0TJgshNIKFkGYoeWUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}