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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee2028d1d36b748bdae757712fb4911a108f16dbcace0a021a2a54dff95f752f' 
  AND token = 'opWmdhuecleTHRyKwAqqII0BmXAUorn1uWcxXn4E5HA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}