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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f93fafc82127aab990b9c5130bfcb1242b699de1bd7429fd9684668d844a25c5' 
  AND token = '0O4Llvis9gnPYTsrUoKmcm80Bo9Ox2m5f3ShTMqdqVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}