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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '472f369f326b2a67883c60ad023b9726f905bffd6a8b0d0cd3ab001492a10de8' 
  AND token = '+3N/m/f3+62saYDRYHsfUn7X5w4Gi6fXyLfZrIX9Ikc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}