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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a638b6917c507b081627c3359f5af6df120aa4f27959858bca558bf18171c8' 
  AND token = 'xf3NfdOloswA/hr8J5Zs5Qyf/QLaxwaeq8HbecbirHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}