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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acfb25e4b1d10c2b62f2fd58a97ffff3b02c93e935486662da6f182dcd008edf' 
  AND token = 'pEyXfkZCg2JNjXvrq6p3mkRnwkltSfgD3n8zsIouI+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}