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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65110725ddb6c8e7a4ba2dff19287ecaeb18ecf70b4de851e3a86ca19e9bd1cd' 
  AND token = 'esqf/59t/wATiqCCeBJMpwq5P523KdqQm7aCIC1CqTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}