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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77cb225b5af226b1208098f688d2a837bfa80a3d922c5f6210486d2de25a16b0' 
  AND token = 'EzkoAB1nnEcRb1jeTRX2cMI8XmuiCmInN0SOlWbFm+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}