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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca7111b201b0572b7cbabc48b213ebfab15a1b6e265839d6a01d673df6f12d27' 
  AND token = 'W97SJzkkMfmJiNRWQII5VMwzUiQet635R1iNtghTDXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}