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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac349b82dc75c65e7eee2cc9d097d1cf3b8a0f1ba8a30e1c2c371dda3c50e39c' 
  AND token = 'uvT5ig1vkm3saSPRzy13+W045aySs5ODtyP560U6yfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}