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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39a3dc086ce26ac3f12f82d8cc687add8bfd57cad297596551ca73532f89c7d2' 
  AND token = '5phnEAM0A0Ngb43BQ2/WvR26YzK522ACBdgTHHzSXQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}