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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39b00f20a3c122b9a30dfcc2656862e8b542dc396ab634b65f4625c3349d81b7' 
  AND token = 'hfSac2HjDoeE+X8EXbytl3yu/fx5jQXIvB7taZ/OYKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}