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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c50cd3d019966afbbc36aea8b1f021a6a04ae1309bf2cd7e603d3c783bb8898' 
  AND token = 'VuqNJCU3BNATLGHC2AS8EJECD9n1BiJoyBUQI+Qj6gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}