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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb25d38259b677d5b95f44a864a23316cce4227e32a1207c7b46329d191f7ffd' 
  AND token = 'r6E5BRMdf7RVgIs1MVhdnUK36U/mPYouUAO/4NAoo/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}