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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e19944ffbac867f53a0be3cd680b8b5575bd0b75b505f0ea5e6da8601746950f' 
  AND token = 'd9XmeWSMUZPqVmHd3bc7Orokgm8rytqbLCOn9aJxROs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}