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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01dcd5bfdeb1f7278ac616a4160606be9c50f054bf453f8226b614d9ce0c6cd3' 
  AND token = 'FRBj6L7Ue2HsuJ40NY//v9ua0Z6qjwW8BHZarvXdkM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}