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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9627c3fac13787c66faaf045ff04ad5e6347ba24e69685052cff00d73cd62a5a' 
  AND token = 'a5cZtQK5FEATEuL8knMapSqWkTiLxH2VXna1eP8xQhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}