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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b34a01c2fcea3149ee60e347f4d08c34593830b5d6611ea189fc9390eec047' 
  AND token = 'e9vXcIcYrxd1dLVox/d0TewkqNstJdwFTkh8SoEYL3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}