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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2e6ca5d1197f192c0689f6f5af1e4a053174e0924c1f0c086888d46c4dbf9ab' 
  AND token = 'u9PdkE5Xl7y3Vujui0ypRSxd/Gfymwh2abc3CHPoC+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}