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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '891c80a07a234dbf88ed10ec1e85b304f90600b912bf3e770994bdeea32799b6' 
  AND token = 'sQjz0pzjfd8B2XR/9uhDNNTOrracIdq5zkYVLGM8B1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}