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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4142e0ce880527fa786d75f96dbfe4497e33ab29f2de066b9ae2f8546cad7427' 
  AND token = 'uZNwCbqndnd3du26KEjLszbhsN7h2h2cNvBWRzmSVuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}