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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ee9c8590f2c205c998e6b11056d7e900d21ded9ca40b740e039adfe96359151' 
  AND token = 'hpwd+/C3ah9qIqr5v4eaRpG7ofS1w846PsbB38NSRvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}