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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fc74f877680dac1dd5458827aafaf8685c5378e56f766ef7d8459196fdca390' 
  AND token = 'Ya22AIwYZLzJ2StKyHw0RBHydibX5sL3Of/Ug/YYmUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}