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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3080b6accf9d3fd757eb548fb83faf62c57941380b868bb9c2fe809da409918c' 
  AND token = 'xYOdVCR/96FC30iKyEMTh3mHqcyTJpGOuDF9sET3bZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}