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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3114cbaef48bc2c04a0737165af10f46ebf534a582205dec26f2c1c9c50d166b' 
  AND token = 'hwipE/dX5U1PWNg8XyITXsrEETjNsYl5GKq8IKcGxHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}