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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef57290dbe865732c353e3ca38b6be8817160dcf471a75592c278903afd9f98b' 
  AND token = 'YgP2u9ZmMc5gRfC9ACy4lrklWAmhQLX8zqFd+hufZaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}