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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc4223cce304d6c1c8091408e33882649f969a0d5c6257c9554179d85321f86b' 
  AND token = 'QxegDklY+VhEjBRmLKaty0c+oPtVpegUPA3TbYjKEu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}