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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7f487092508cc36cd69f4f7e37047edcf3159e7a2f8e320fac66a27bcf2bb93' 
  AND token = 'OQE3fJo3aEGkdlUnANblx8Q2AVEbyNPRGdqzbq1CIxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}