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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '617de49f71c70f06f652c4a48d4798a5604f42ddff9dc5253dcbdd7f42a09d26' 
  AND token = '5MfJcAWC51rN8s5UhT43u8Wlt3Nxxx+GOz8Qgsm9vyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}