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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b2a2b789491c0ffe5428737862ff96b77eab2a7681f9c1fef82b7fa0e27240b' 
  AND token = 'AGIyF+L/ZmhZNMyIHSntC4ZFVXg2CIPA9hHitMA2Y9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}